Nu Instruments | Nanoparticle Analysis Using Attom ES at 10⁵ Hz Acquisition Rates
This application note explains how Attom ES supports nanoparticle analysis using fast acquisition rates and flexible peak integration. It shows how Nu Quant processes transient nanoparticle signals across different dwell times and particle shapes.
Nanoparticle signals in ICP-MS are short, often lasting only hundreds of microseconds. Conventional millisecond dwell times may miss important signal detail, while shorter dwell times can create new challenges in data volume and dynamic range.
Attom ES can acquire single ion data with dwell times as low as 10 μs without interruptions. Multiple methods can be linked together, allowing samples to be analysed under different conditions in an automated sequence.
Nu Quant uses smoothing, peak search and flexible integration routines to process complex nanoparticle data. It can accommodate different particle widths, partially merged peaks and background signals while supporting NICE-based calculations for size, mass and concentration.
Key Takeaways:
- Attom ES enables uninterrupted nanoparticle acquisition at up to 10⁵ Hz.
- Nu Quant integrates particles with varied peak shapes and dwell times.
- NICE scripts support calculation of particle size, mass and concentration.
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