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Life Sciences

Advance Life Science Research with High-Precision Elemental and Isotopic Analysis

Supporting new research areas in Life Sciences 

Generate deeper biological, biomedical, and environmental insights through accurate isotopic and trace element measurements across complex life science samples.

From biomarker studies and metabolic research to trace element analysis and isotope tracing, Nu Instruments provides advanced ICP-MS and IRMS solutions designed to deliver high-quality analytical data for life science investigations.

 

Life science research increasingly relies on sensitive elemental and isotopic measurements to understand biological processes, disease mechanisms, nutrient cycling, and therapeutic development. High-performance mass spectrometry enables researchers to investigate trace elements, isotopic signatures, metabolic pathways, and biological interactions with greater analytical confidence across a wide range of sample types.

Featured Publications

Vitesse Application note booklet

Measuring Metal-Tagged Markers and Endogenous Elements in Single Cells

The simultaneous measurement of metal-tagged biomarkers and endogenous elements in individual cells. Researchers can identify cell populations, quantify elemental content at the single-cell level.
Read Application Note
Sapphire Application note booklet

Precise Calcium Isotope Determination with Dual-Path MC-ICP-MS

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Read Application Note
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HR-ICP-MS, MC-ICP-MS

Trace Element Analysis in Biological Samples

Understanding the role of trace and ultra-trace elements in biological systems is critical for advancing research in human health, nutrition, toxicology, and environmental exposure assessment. Researchers routinely analyse tissues, blood, urine, plant materials, and other biological matrices to investigate elemental imbalances, nutrient uptake, metal toxicity, and disease-related changes. Accurate elemental measurements at extremely low concentrations enable scientists to generate reliable datasets that support both fundamental biological research and applied health studies.

Learn about HR-ICP-MS
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ICP-TOF-MS, MC-ICP-MS

Metallomics and Metal-Based Biomarker Research

Metallomics focuses on understanding the role, distribution, and transformation of metals within biological systems. Researchers investigate how essential and toxic elements interact with proteins, metabolites, cells, and tissues to influence biological function, disease progression, and therapeutic response. These studies are increasingly important in areas such as neurodegenerative disease research, cancer biology, nutrition, toxicology, and precision medicine.
Advanced ICP-MS and TOF-ICP-MS techniques enable the sensitive detection of trace metals while supporting comprehensive multi-element analysis across complex biological samples. High-speed simultaneous elemental acquisition can reveal subtle changes in metal homeostasis, elemental interactions, and metal-based biomarkers, helping researchers gain deeper insight into the relationship between metal chemistry and human health

Learn about ICP-TOF-MS
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HR-ICP-MS, MC-ICP-MS

Biomedical and Clinical Research

Modern biomedical research requires analytical technologies capable of detecting small but significant changes in elemental and isotopic composition across a wide range of biological samples. Researchers use these measurements to investigate disease mechanisms, identify potential biomarkers, evaluate therapeutic interventions, and better understand physiological processes at both the molecular and systemic level.
Applications range from investigating metal homeostasis in neurodegenerative disorders to examining nutrient utilisation, drug distribution, and metabolic responses in clinical and translational research. The ability to generate reproducible, high-quality analytical data is essential for supporting robust scientific conclusions and accelerating discovery.

Learn about MC-ICP-MS
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TOF, HR-ICP-MS

Imaging and Nanomedicine Research

The growth of nanotechnology and spatial biology has created increasing demand for techniques capable of visualising elemental distributions within biological systems. Researchers seek to understand where specific elements, nanoparticles, and therapeutic compounds accumulate within tissues, cells, and organs to better evaluate biological function, treatment efficacy, and potential toxicity.
Advanced ICP-MS imaging techniques enable detailed investigation of elemental localisation at high speed and sensitivity, supporting applications in nanomedicine, drug delivery, toxicology, and biomedical materials research. By combining spatially resolved elemental information with quantitative analysis, scientists can gain a deeper understanding of complex biological interactions.

Learn about TOF
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