Nu Instruments | Long-Term Signal Stability in Wet and Dry Plasma ICP-MS Analysis 

This application note compares long-term analytical stability under wet and dry plasma operating conditions. Results demonstrate reliable unattended operation during extended analysis sessions.

Details for both experiments.

Stable sample introduction is essential for obtaining reliable ICP-MS results. Variations in nebulisation, sample matrices and instrumental factors can affect long-term performance.


The Attom HR-ICP-MS was evaluated over extended analytical periods using both traditional wet plasma and desolvated dry plasma sample introduction systems. Multiple rhenium standards were analysed without user intervention.


Signal stability remained excellent throughout the experiments, with relative standard deviations below 2% for wet plasma and below 3% for dry plasma. These findings support routine high-precision analytical applications.

Attom HR ICP-MS Instrument

Key Takeaways:

  • Excellent long-term stability during unattended operation.
  • Consistent performance in both wet and dry plasma modes.
  • Supports reliable trace element and isotope ratio measurements.
Man adjusts part of mass spec instrument

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